Trusted by 45,000+ women
Midlife Support Duo: Progesterone 50 mg + Bi-Est 2.5 mg Bundle
Midlife Support Duo: Progesterone 50 mg + Bi-Est 2.5 mg Bundle
Balanced Hormones - Better Living
- Supports women through perimenopause + menopause.*
- Features bioidentical progesterone + Bi-Est for balanced support.*
- Designed to support mood, skin, and overall well-being.*
- Topical hormone support made with clean, nourishing ingredients.*
- Includes aloe, coconut oil, and shea butter for smooth absorption
- A simple daily ritual for midlife balance + vitality.*
Creams are intended for external cosmetic use only.
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Expected delivery: 3–5 days (U.S. domestic)
Next-day and 2-day shipping are not guaranteed for weekend orders
HSA/FSA Eligible

Reclaim Your Balance, Revitalize Your Life
Renewed Vitality
Feel refreshed and ready to take on your day with a soothing, fast-absorbing creams that help you feel your best.*
Improved Energy Levels
Feel recharged and ready to take on your day
Monthly Comfort
Formulated to bring ease and comfort during your natural monthly rhythm — so you can feel more like yourself.*
Transition Support
Designed for women navigating life’s natural changes, helping you feel centered and comfortable through every phase.*
Calm & Collected
Promotes a sense of relaxation and ease for a balanced, peaceful state of mind.*
Results You’ll Love - Here’s the Proof
Before
After
“My energy levels are up, I feel more balanced overall”
-Jessica, 45 years
3 months ago
- Mood swings
- Poor sleep
- sluggish metabolism
Now
- Boosted energy
- Clearer mind
- boosted metabolism
Before
After
“The Raena Natural Progesterone has been a lifesaver!"
-Tamara, 65 years
3 months ago
- Irregular periods
- Mood swings
- Low libido
Now
- More regular periods
- Improved mood stability
- Increased libido
Before
After
“The Raena Natural Progesterone has been a lifesaver!"
-Alannah., 30 Years
3 months ago
- Mood swings
- Low libido
- Low Energy
Now
- More regular periods
- Improved mood stability
- Increased libido
Free shipping for orders over $100
7 Clues You Need Progesterone Cream
Mild Irregular Cycles
Mild Mood Swings or Irritability
Occasional Sleep Disruptions
PMS or PCOS Symptoms
Low Libido or Low Energy
Breast Tenderness or Mild Lumps
Post-Menopausal Discomfort
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
Simple, Effective, Hassle-Free
APPLY DAILY
For women no longer having a menstrual cycle, apply progesterone + Bi-Est daily for ongoing hormone support.
or USE AS NEEDED
Bi-Est can also be used during moments of increased symptoms or discomfort for added support. Meanwhile women love progesterone daily when they don't have a cycle.
See Results
Start noticing changes within 2–4 weeks
No Artificial Dyes
No Peanut Oil
No Titanium Dioxide
No Fillers, Just Pure Balance
Our bioidentical hormones match your body’s natural balance for better absorption and fewer side effects—because your health deserves the best.
Evidence-Backed Active Ingredients
Progesterone
Pure, bioidentical hormone for balance
Vitamin E
Boosts absorption and protects cells*
coconut oil
Promotes skin health*
Aloe Vera
Soothes irritation, hydrates deeply*
All Ingredients
All Ingredients
See the Difference Our Community Reports Over Time
- Fall asleep faster and stay asleep longer
- Wake up feeling more refreshed
- Improved sleep-wake cycle
- Enhanced dream quality and mental clarity in the morning
- Fewer nighttime awakenings
- Deeper, more restorative sleep
- Consistently restful nights
- Steady energy levels and better focus throughout the day
- Better sleep
- More calm, less anxiety
- Cycle feels more regular
- Reduced irritability
- No abdominal bloating
- Lighter cramps
- Balanced hormones
- Steady energy throughout the day
- Reduced breast tenderness
- Fewer headaches
- Better sleep
- Reduced irritability
- No abdominal bloating
- Lighter cramps
- Balanced hormones
- Steady energy throughout the day
- Calmer, more stable mood
- Fewer mood swings and emotional highs and lows
- Cycle feels more regular
- Reduced irritability
- Clearer thinking and improved focus
- Enhanced emotional resilience and calm
- Consistently balanced mood
- Steady energy and a positive outlook throughout the day
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
Backed by Research, Trusted by Women
of women felt report being satisfied, very satisfied, or more than satisfied with our solutions
of women reported better sleep after 2 weeks of use
Why Raena is Your Natural Hormonal Choice
Mimics Natural Hormones
Made with Plant-Based Ingredients
Addresses Root Causes*
Supports Long-Term Wellness*
Customizable to Individual Needs
Synthetic Hormones