Trusted by 30,000+ women
Raena Bi-Est 2.5mg
Raena Bi-Est 2.5mg
Balanced Hormones - Better Living
- Helps maintain a sense of comfort during life’s natural transitions*
- Promotes relaxation and well-being*
- Nourishing cream formulated for topical comfort and balance*
This cream is intended for external cosmetic use only.
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Expected delivery: 3–5 days
HSA/FSA Eligible

Reclaim Your Balance, Revitalize Your Life
Renewed Vitality
Feel refreshed with a fast-absorbing cream designed to support daily balance and well-being.*
SOOTHING COMFORT
Formulated to help you feel cool, calm, and collected through life’s transitions.*
TRANSITION SUPPORT
Crafted with gentle plant-based estrogens to nurture comfort and balance during midlife.*
SKIN NOURISHMENT
Hydrates, softens, and promotes a healthy glow for skin that feels supple and smooth.*
Results You’ll Love - Here’s the Proof
Before
After
“My energy levels are up, I feel more balanced overall”
-Tamara, 65 years old
3 months ago
- Hot flashes
- Poor sleep
- sluggish metabolism
Now
- Boosted energy
- Clearer mind
- boosted metabolism
Before
After
"I dab a little bit as I need it and it's amazing for my energy levels."
-Jessica K., 45 Years
3 months ago
- Low libido
- Low Energy
- Hot Flashes
Now
- Improved mood stability
- Increased libido
- No Hot Flashes
Free shipping for orders over $100
7 Signs You Might Love Raena Bi-Est
Shifts in comfort or temperature balance
Feeling less vibrant than usual
Occasional restlessness or disrupted sleep
Desire for smoother, more hydrated skin
Fluctuating confidence or mood
Changes in daily energy
Seeking a sense of renewed balance
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Sleep Problems
Simple, Effective, Hassle-Free
Apply Daily
If you no longer have a menstrual cycle
START YOUR DAY RIGHT
Best applied in the morning
See Results
Start noticing changes within 2–4 weeks
No Artificial Dyes
No Peanut Oil
No Titanium Dioxide
No Fillers, Just Pure Balance
Our bioidentical hormones match your body’s natural balance for better absorption and fewer side effects—because your health deserves the best.
Evidence-Backed Active Ingredients
ESTRIOL (E3)
Gentle, plant-based estrogen for topical nourishment and skin comfort*
ESTRADIOL (E2)
Helps maintain smooth, hydrated skin and overall balance*
VITAMIN E
A natural antioxidant that supports healthy-looking skin*
Coconut Oil
Moisturizes and softens for a luxurious feel*
All Ingredients
All Ingredients
See the Difference Each Week Brings
- Feel refreshed and comfortable as your skin begins to absorb and hydrate*
- Enhanced moisture and more consistent comfort through your day.*
- Notice smoother texture and an increased sense of calm.*
- Continued balance, radiance, and confidence with daily use.*
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Slwep Problem
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Slwep Problem
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Slwep Problem
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Slwep Problem
No Peanut Oil
No Titanium Dioxide
No Red or Yellow Dye
No Slwep Problem
Backed by Research, Trusted by Women
of women reported being satisfied, very satisfied, or more than satisfied with our solutions.
of women reported better sleep after 2 weeks of use.
Why Raena is Your Natural Hormonal Choice
Mimics Natural Hormones
Made with Plant-Based Ingredients
Created for everyday comfort*
Designed for long-term topical support
Customizable to Individual Needs
Synthetic Hormones